The Kaiser Papers A Public Service Web SiteIn Copyright Since September 11, 2000
This web site is in no manner affiliated with any Kaiser entity and the for profit Permanente
Link for Translation of the Kaiser Papers 
PATHFINDER(search)  |   ABOUT US  |  CONTACT  |  WHY THE KAISERPAPERS  |  

biotechnology.kaiserpapers.info

Scientific Documentation alerting to the potential danger of  GMO's and related biologicals



http://www.epa.gov/oppbppd1/biopesticides//ingredients/factsheets/factsheet_129084.htm#humanhealth
 and explained in layman terms here:

http://www.nysaes.cornell.edu/ent/biocontrol/pathogens/lagenidium_giganteum.html

There are many studies refuting the alleged safety of this fungi or zoospore.  Lagenidium Giganteum is a lifeform that is known to eat bugs, particularly mosquitos from the inside out.  Lagenidium giganteum is not a pesticide - it is a fungus type organism that once was known to live only in a remote part of the SouthEastern US!  It kills by eating the host from the inside out.

Medical/Scientific Documentation explaining the danger of these products



An oomycotic pathogen in the genus Lagenidium was isolated from tissues....

Is AG Biotechnology Safe or UnSafe? - Genetically Modified/Engineered Organisms - Flyer

See also:
: U.N. - Tue May 27, 2008
- Reuters
Mirrored here for historical purposes.
biotechtrade.html

The following study on dogs show that it isn't very good for them either.

An oomycotic pathogen in the genus Lagenidium was isolated from tissues....

CHARACTERIZATION OF A PREVIOUSLY UNDESCRIBED LAGENIDIUM PATHOGEN ASSOCIATED WITH SOFT TISSUE INFECTION: INITIAL DESCRIPTION OF A NEW HUMAN OOMYCOSIS
"Immunoblot analysis of the serologic response of three affected dogs to soluble mycelial extracts of L. giganteum and of the previously described pathogenic Lagenidium species was performed, and indicated that each dog’s serum recognized a large number of antigens of both Lagenidium species"

- The best known species of Lagenidium is Lagenidium giganteum, a parasite of mosquitolarvae used in biological control of mosquitoes. Two different species cause disease exclusively in dogs:L. caninum and L. karlingii. Lagenidiosis is found in the southeastern United States in lakes and ponds. It causes progressive skin and subcutaneous lesions in the legs, groin, trunk, and near the tail. The lesions are firm nodules or ulcerated regions with draining tracts. Regional lymph nodes are usually swollen. Spread of the disease to distant lymph nodes, large blood vessels, and the lungs may occur.[7] An aneurysm of a great vessel can rupture and cause sudden death.[17] L. caninum is the more aggressive species and is more likely to spread to other organs than L. karlingii.[2

Contary proven scientific documentation the FDA has reported that this is a safe lifeform for humans to ingest.

Pythiosis in the Dog, Horse and Cat and Lagenidiosis in the Dog
Oomycetes cause disease when animals with damaged skin come into contact with zoospores, which encyst in the exposed tissue.(Pythiosis is an uncommon cutaneous/subcutaneous, gastrointestinal, or multisystemic disease caused by a water mold. It has been reported in dogs, horses, cats, cattle, humans and a captive zoo bear.An as yet undetermined species of Lagenidium is responsible for lagenidiosis in dogs. The genus Lagenidium includes more than 50 species of which most are natural parasites of algae, fungi, rotifers, nematodes, crustaceans, Daphne, and mosquito larvae. L. giganteum, a parasite of mosquito larvae, has been approved by the Environmental Protection Agency for use in the United States as a biological control of the adult mosquito population.)  Oomycetes cause disease when animals with damaged skin come into contact with zoospores, which encyst in the exposed tissue.


Bacillus Subtilis  is another Agraquest grown product.
These two documents, prepared and submitted by David Bell's Qualified Medical Examiner (QME), DR NG for the Workers' Compensation case of David Bell CLEARLY shows there is indeed RISKS associated with being around Bacillus Subtilis (FOUND ON NUMEROUS PATENTS ISSUED TO AGRAQUEST, INC. BY THE UNITED STATES PATENT OFFICE AS WELL AS INTERNATIONAL PATENTS). 

DR NG STATES: "Nonetheless, he had no history of requiring any surgery until his work at AgraQuest, Inc. It is therefore within medical probability that his exposure at work has aggravated his allergic rhinitis which in turn exacerbated his sinusitis resulting in the need for surgery in 1/99."

Dr. Nagy and
 Dr. V.A. Marinkovich's expert medical opinions, based on proven scientific literature clearly shows the relation of David Bell's iinjury/illness/disease to the Agraquest
Research and Development Company. See: http://biotechnology.kaiserpapers.info/intheory.html

In the interest of public safety and because this product is being grown to kill life forms by the company AgraQuest, the information on bacillus Subtilis is also provided here.

 
There are numerous scientific articles as to Bacillus Subtilis NOT being safe and indeed causing disease and illness.
One of these articles is  the 1997 EPA Final Risk Assessment on Bacillus Subtilis. 

Some of the others do include but are not limited to:
(Flindt et al., Pulmonary disease due to inhalation of derivative of bacillus subtilis containing  
proteolytic enzymes,Lancet I: 1177-1181], 1969) About the same time, Pepys & Coworkers studied three workers  with work-related asthmatic symptoms who were exposed to B subtilis-derived enzymes (Pepys 1969, Allergic reaction of the lungs to enzymes of bacillus subtilis and Lancet I, 1811-1814). 

These workers had prick test reactivity to B-subtilis alcalase and maxatase and exhibited both immediate and lape phase asthmatic response following inhalation challenges.  A study performed in the United States on 38 detergent workers identified immediate onset upper respiratory tract, nasal and ocular symptoms in 11 workers and no respiratory symptoms in 25 workers, which often begins 3-8 hours after leaving work. (Franz et al.,  Clinical, immunologic, and physiologic observation in factory workers exposed to B-subtilis enzyme dust, Journal of Allergies 47; 170-179}. 

There is data in the literature associating  exposure to bacillus subtilis products and respiratory disease as well as rhino conjunctivitis, (Kaner et al., Contact Dermatitis 2001, 45: 49-51, Flindt et al., Occupational Medicine, Volume 52, 2002). 
The best known species of Lagenidium is Lagenidium giganteum, a parasite of mosquito larvae used in biological control of mosquitoes. Two different species cause disease exclusively in dogs: L. caninum and L. karlingii. Lagenidiosis is found in the southeastern United States in lakes and ponds. It causes progressive skin and subcutaneous lesions in the legs, groin, trunk, and near the tail. The lesions are firm nodules or ulcerated regions with draining tracts. Regional lymph nodes are usually swollen. Spread of the disease to distant lymph nodes, large blood vessels, and the lungs may occur.[7] An aneurysm of a great vessel can rupture and cause sudden death.[17] L. caninum is the more aggressive species and is more likely to spread to other organs than L. karlingii.[2
Agraquest's products containing bacillus subtilis have a FOUR (4)  hour RE-ENTRY time.  Meaning lab personnel being exposed to this in the laboratory did not have the luxury of that FOUR 94) hour RE-ENTRY time.

The 4/1999 and 6/1999 submission to the Environmental Protection Agency (EPA) by Agraquest of "new active ingredient" (QST713 - bacillus subtilis) only received a "CONDITIONAL TIME-LIMITED REGISTRATION from the EPA on 6/20/2000 (Janet L. Anderson, Ph.D, Director - Biopesticides and Pollutions Preventon Division) as the EPA themselves found fault.... Storage Stability, Manufacturing Process - toxicity/pathogenicity to; Freshwater Fish, Freshwater aquatic invertebrate, paleomonetes vulgaris (shrimp) and HONEY BEES.

ADDITIONALLY, Identification and Characterization of Novel Genetic Markers Associated with Biological Control Activities in Bacillus subtilis -Raghavendra Joshi and Brian B. McSpadden Gardener Department of Plant Pathology, The Ohio State University, OARDC, 1680 Madison Ave., Wooster 44691. 
Accepted for publication 3 October 2005.

DISCUSSION:  Nearly half of the 149 sequences we analyzed were sufficiently different from those presently in GenBank that no functional assignments could be made

Identification of subtracted genome fragments obtained from Bacillus subtilis QST713 [AGRAQUEST]
Bacillus amyloliquefaciens
Bacillus  cereus
Bacillus  licheniformis
____
2)

NOT all forms of Histoplasmosis are curable as can be found within the CDC, NIOSH just to name a few.  It has been well documented in numerous scientific publications that the disease Histoplasmosis (caused by Histoplasma Capsulateum) can indeed be and has been fatal to humans. 

Histoplasma is NOT only (found) caused by bat guano or bird droppings.  It is well known this fungi is found in soil as well
Mirrored here for historical purposes is self reported information by the creator of these companies that does alter DNA bacterias and fungi for the purpose of  calling their products natural insecticides.  How natural a genetically altered bacteria or fungi can really be is a good question?  Probably it is as natural as any chemical insecticide that is also created from parts of this earth.  The word natural means not altered, not produced artificially, or conforming to the usual or ordinary course of nature.  

KAISERPAPERS.INFO